正常人各方位视网膜神经纤维层厚度值的测量  

Quantification of Retinal Nerve Fiber Layer Thickness in Different Orientation in Normal Subjects

作　　者：凌运兰[1] 刘杏[1] 郑小平[1] 

机构地区：[1]中山医科大学中山眼科中心,广东广州510060

出　　处：《中山医科大学学报》2001年第3期212-214,224,共4页Academic Journal of Sun Yat-sen University of Medical Sciences

基　　金：广东省科委重点项目基金 ( 9849)

摘　　要：【目的】应用光学相干断层成像术 (OCT)测量我国正常人视网膜神经纤维层 (RNFL)各钟点范围厚度值和平均值 ;分析RNFL各钟点范围厚度值之间的差异及其与年龄、性别、眼别之间的关系。【方法】用OCT对 10 4例 (183眼 )正常人进行以视乳头为中心的环行扫描 ,扫描直径 3 46mm ,记录平均和各个钟点范围的RNFL厚度值并分析其与年龄、性别和眼别的关系。【结果】正常人以 10 :30～、11:30～、12 :30～、1:30～、2 :30～、3:30～、4:30～、5 :30～、6 :30～、7:30～、8:30～、9:30～ 12个钟点范围测量的RNFL厚度 (μm)分别为 144± 14、141± 16、135± 12、10 4± 17、78± 15、90± 18、130± 16、147± 17、145± 13、92± 16、80± 11、10 3± 10 ,而全周平均RNFL厚度值则为 (116± 5 ) μm。颞上 (10 :30～ 12 :30 )、颞下 (5 :30～ 7:30 )和平均RNFL厚度均与年龄呈负相关 (P值为 0 0 0 5～ 0 0 0 0 )。不同性别各钟点范围及平均RNFL厚度均数的比较 ,差异无显著性 (P值为 0 35 6～ 0 781)。正常人左、右眼各钟点范围及平均RNFL厚度之间差异亦无显著性 (P值为 0 15 5～ 0 6 12 )。【结论】正常人各钟点范围RNFL厚度以颞上 (10 :30～ 12 :30 )和颞下 (5 :30～ 7:30 )最厚 ,鼻侧 (2 :30～ )和颞侧To measure RNFL thickness (clock type and mean) and investigate the relationship between RNFL thickness and age, gender, and right or left eye in normal subjects using OCT. OCT was used in 183 eyes of 104 normal subjects to measure RNFL thickness with circle scan (scan diameter of 3 46mm) around optic nerve head. RNFL thickness (μm) measured by OCT in normal eyes according to clock type (10:30～?11:30～?12:30～?1:30～?2:30～?3:30～?4:30～?5:30～?6:30～?7:30～?8:30～?9:30～) were 144±14?141±16?135±12?104±17?78±15?90±18?130±16?147±17?145±13?92±16?80±11?103±10, respectively,and mean of whole circle was (116±5) μm. There was a negative correlation between RNFL thickness in temple superior (10:30～12:30), temple inferior (5:30～7:30), mean thickness and age (P=0 005～0 000). There was no significant differences between RNFL thickness of various clock and mean (P=0 356～0 781), gender and right or left eye (P=0 155～0 612). [Conclusion] RNFL thickness was thicker in temple superior (10:30～12:30) and temple inferior (5:30～7:30), thinner in nasal (2:30～) and temple (8:30～) in normal subjects. The elder of persons, the thinner of RNFL thickness. RNFL thickness was not related to gender and right or left eye.

关 键 词：断层扫描 视网膜 神经纤维层 厚度值 测量 

分 类 号：R339.141[医药卫生—人体生理学] R774[医药卫生—基础医学]