SPECT脑灌注显像探测SLE脑内损伤的价值  

Value of cerebral blood flow perfusion SPECT imaging in subacute lugus erythematosus

作　　者：修雁[1] 孙晓光[1] 陈绍亮[1] 刘文官[1] 李文罡[1] 姜林娣[1] 

机构地区：[1]复旦大学医学院上海中山医院,上海200032

出　　处：《核技术》2001年第5期381-384,共4页Nuclear Techniques

摘　　要：为探讨SPECT脑血流灌注显像诊断SLE脑部受损的价值 ,分别对 18例SLE患者和 11例正常对照组进行了SPECT脑血流灌注显像 ,采用肉眼读片分析及半定量分析进行评价。其中 5例患者进行CT和 或MRI检查。结果表明 ,肉眼读片分析SPECT诊断SLE脑部受损的灵敏度为 67.7% ,半定量分析的灵敏度达 70 % ,CT灵敏度只有 2 0 %。不配对t检验示扣带回、颞顶叶等部位最常受累。说明SPECT脑血流灌注显像有助于发现SLE患者脑部血流受损情况。To evaluate cerebral blood flow perfusion SPECT imaging in SLE brain invovlement. Cerebral blood flow perfusion SPECT imaging was performed in eighteen SLE patients and 11 controls. The results were analyzed by vision and semiquantitative comparison. Five of them performed CT and/or MRI scan also. The sensitivity of SPECT imaging by vision and semiquantitative analysis was 67.7%, and 70% respectively and only 20% for CT scan. Cingulate gyrus and temporal-parietal was most involved area under unpaired t -test. The sensitivity of cerebral blood flow perfusion SPECT imaging was high, but lack of specificity.

关 键 词：SLE 脑血流灌注显像 SPECT 系统性红斑狼疮 诊断 脑内损伤 

分 类 号：R817.4[医药卫生—影像医学与核医学] R593.241[医药卫生—放射医学]