血浆总同型半胱氨酸在心肌梗死患者中的水平  

The level of total homocysteic acid in patients with myocardial infarction

作　　者：牛建英[1] 王瑞英[1] 李清[1] 

机构地区：[1]山西医科大学第二医院心内科,太原030001

出　　处：《临床心血管病杂志》2001年第5期204-205,共2页Journal of Clinical Cardiology

摘　　要：目的 :研究心肌梗死 (MI)患者血浆总同型半胱氨酸 (t HCA )的水平及其临床意义。方法 :利用荧光偏正免疫分析法测定 30例 MI患者和 2 0例正常人血浆 t HCA的浓度 ,同时分析 t HCA浓度与吸烟史、糖尿病、高血压以及各血脂指标之间的关系。结果 :MI患者血浆 t HCA的浓度较正常人明显增高 ;冠状动脉病变的支数越多 ,t HCA的浓度越高 ;吸烟、糖尿病、高血压及其血脂各指标与 t HCA之间均无明显的相关关系。结论 :高血浆t HCA血症可能是致 MI的一个重要危险因素。Objective:To study the level and clinical significance of plasma total homocysteic acid(tHCA) in patients with myocardial infarction(MI). Method:Plasma tHCA on 30 patients with MI and 20 normal peoples were measured by FPIA technology.The relations among tHCA and cigarette smoking, diabetes, hypertension and blood lipid were analysed. Result:The level of plasma tHCA on patients with MI was higher than that of the control group. The more coronary arteries involved the higher plasma tHCA. There were no association among tHCA cigarette smoking, diabetes, hypertension and blood lipid. Conclusion:High plasma tHCA may be an independent risk factor for MI.

关 键 词：心肌梗死 血浆 总同型半胱氨酸 tHCA 

分 类 号：R542.22[医药卫生—心血管疾病]