胆道厌氧菌感染的临床与实验研究  

Clinical and Experimental study of Anaerobic Bacterial Infection of Biliary Tract

作　　者：李宁[1] 肖路加[1] 陈晓礼 范昕建[2] 肖邦良[3] 程薇波[3] 

机构地区：[1]华西医科大学附一院外科 [2]华西医科大学附一院内科 [3]华西医科大学公共卫生学院

出　　处：《华西医学》1991年第3期336-338,共3页West China Medical Journal

摘　　要：在临床研究的基础上,作者制成厌氧菌胆道感染的兔模型。120只日本杂交大耳白兔随机分为4组:对照组14只,脆弱类杆菌组31只,大肠杆菌组44只,混合感染组33只。术后7、15、30天存活兔处死并作不同检查。病理发现,需氧菌与厌氧菌均能导致肝胆系统上皮浊肿,空泡变性,水样变性及坏死脱落,粘膜下出现新生腺体。厌氧菌可导致肝胆系统内之脓肿形成和腹壁切口之感染。On the basis of the clinical study, A rabbit's model of anaerobic bacterial infection of biliary tract was established. One hundred and twenty Japanese hybrid big-ear white rabbits randomized in four groups: 14 in control group, 31 in B. fragilis group 42 in E.coli group and 33 in mixed infection grcup. At the 7, 15and 30 postoperative days, the survial rabbits were sacrificed for different investigations. In the pathologic studies, both aerobic and anaerobic bacterial infection could develop severe pathologic changes in the hepato-biliary systems including cloudy swelling, vacuolar degeneration, hydropic degeneration and necrosis. The bacterial infection might cause large amount of new propliferative glands in the submucos of bile ducts and gallbladders. The incidence of absecss formation in the hepato-biliary system and the incisional infection on abdominal wall was much higher in the anaerobic bacterial group.

关 键 词：厌氧菌 感染 胆道 

分 类 号：R446.5[医药卫生—诊断学]