卵巢巧克力囊肿保守性手术后检测异位内膜组织中雌孕激素受体指导用药的探讨  

Test Estrogen and Progesterone Receptors of Ectopic Tissue in Ovarian Chocolate Cyst After Conservative Operation to Select Medicine

作　　者：黄学惠[1] 李武[1] 董文漪[1] 

机构地区：[1]昆明医学院第一附属医院,云南昆明650032

出　　处：《实用妇产科杂志》2001年第3期157-158,共2页Journal of Practical Obstetrics and Gynecology

摘　　要：目的 :探讨ER、PR在子宫内膜异位症治疗方面的意义。方法 :ER、PR的测定用免疫组化SP法。治疗组术后根据受体情况分别给予丹那唑、TMX、或安宫黄体酮治疗 ,对照组术后未用药。结果 :卵巢巧克力囊肿患者增生期和分泌期ER、PR的阳性率均低于正常子宫内膜 (P <0 0 5 )。治疗组无一例复发 ,而对照组复发率为 2 4%。结论 :根据卵巢异位内膜囊肿患者术后受体情况 ,进行药物巩固治疗 ,对于防止术后复发 ,提高治愈率有一定的意义。Objective:To explore the significance of estrogen receptor(ER)and progesterone receptor(PR)of in treatment of endometriosis.Methods:ER and PR were measured with immunohistochemical streptavidin perovdase conjugataed method.The treatment group were given danazol,Tamerxifen or Medroxyprogesterone according to their ER、PR after conservative operation.And the control group were not use medicine after operation.Results:The positive rate of estrogen and progesterone receptor in proliferative and secretory phase in ovarin endometria cyst were lower than normal endometrium ( P <0 01).No one of treatment group was recurrent.The recurrence rate of control group was 24%.Conclusions:It is importance that use different medicine according to ER、PR of tissue in ovarian chocolate cyst to prevent recurrence and promote cure rate after conservative operation.

关 键 词：卵巢巧克力囊肿 雌激素受体 孕激素受体 药物治疗 子宫内膜异位 

分 类 号：R711.71[医药卫生—妇产科学]