补肾延年丹对老年大鼠全血细胞DNA修复能力的影响  

Effect of Bushen Yanman Granule on DNA Repair Capacity in Whole Blood Cells of Old Rats

作　　者：郭语彬[1] 张克纯[1] 徐桂香[1] 刘群良[1] 阳力争[1] 周文泉[1] 张国玺 高普 

机构地区：[1]湖南中医学院生化教研室,中国中医研究院西苑医院

出　　处：《中国实验方剂学杂志》1995年第2期25-28,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：补肾延年丹对老年大鼠全血细胞非程序ＤＮＡ合成（ＵＤＳ）的实验结果表明：４０秒ＵＶ诱导下大鼠全血细胞ＵＤＳ各组间差异无显著意义（Ｐ＞０．ｈ）．８０秒ＵＶ诱导下大鼠全血细胞ＵＤＳ各组间差异有显著意义（Ｐ＝０．０５），补肾延年丹大、中、小剂量组ＵＤＳ均高于老年空白对照组，说明补肾延年丹能提高老年大鼠对ＵＶ损伤时ＤＮＡ的修复能力。The effect of Bushen Yannian granule on unscheduled DNA synthe-ses(UDS)in whole blood cells of old rats was studied. The results showed that UDS in the group treated with Bushen Yannian granule at a high,or moderate,or low dose,was higher than that in the old control group(P<0.05),indicating that it can enhance DNA repair capacity in old rats.

关 键 词：补肾延年丹 DNA修复能力 非程序DNA合成 实验研究 

分 类 号：R285.5[医药卫生—中药学]