杀鼠灵对映体的高效毛细管电泳手性拆分  

Enantiomeric Separation of Dethmor by High Performance Capillary Electrophoresis

作　　者：游静[1] 陆豪杰[1] 姜廷福[1] 欧庆瑜[1] 

机构地区：[1]中国科学院兰州化学物理研究所502组,甘肃兰州730000

出　　处：《分析测试学报》2001年第3期59-61,共3页Journal of Instrumental Analysis

摘　　要：以磺丁基_β_环糊精作为手性添加剂利用毛细管电泳成功地分离了杀鼠灵对映体 ,并系统地考察了磺丁基_β_环糊精浓度、缓冲溶液pH值、缓冲溶液浓度、有机添加剂种类和浓度以及电压等分离条件对其分离的影响。发现通过利用带电环糊精 ,调节分离条件 。The enantiomers of Dethmor were successfully separated by high performance capillary electrophoresis using sulfobutyl ether β _ cyclodextrin as a chiral selector. Effects of the concentration of sulfobutyl ether β _ cyclodextrin, pH and concentration of the buffer, type and concentration of organic modifier, and voltage on the resolution of Dethmor enantiomers were investigated. By changing separation conditions, the order of the two peaks can be controlled conveniently.

关 键 词：高效毛细管电泳 磺丁基-β-环糊精 杀鼠灵 对映体 手性折分 杀鼠药 分离 

分 类 号：TQ456[化学工程—农药化工] TQ450.7