室温快速固化医用聚氨酯扩链剂的反应性及产物性能研究  

A Rapid Room-solidification Reaction of Expander and the Prepolymer for Medical Polyurethane and Its Properties

作　　者：彭平[1] 李效东[1] 肖绍博 赵生才 史双来 方志薇[1] 廖杰[1] 刘长虹[1] 李盛[1] 岳曼君[1] 

机构地区：[1]国防科学技术大学材料科学与应用化学系,长沙410073 [2]国家计划生育委员会科技司,北京100088 [3]山西省生育调节中心,太原030012

出　　处：《北京生物医学工程》2001年第2期135-139,142,共6页Beijing Biomedical Engineering

基　　金：国家计生委"九五"重点攻关课题

摘　　要：在研究快速固化医用聚氨酯材料中 ,制备了以脂肪族多元醇为主的混合扩链剂 (NB)。以芳香二胺MOCA为主的商品扩链剂 (MB)作参照物 ,用红外光谱和凝胶色谱分别对NB和MB与聚醚型聚氨酯预聚体的反应过程进行了跟踪分析 ,并研究了各自所生成的聚氨酯材料N PU和M PU的性能。结果表明 :N PU中的异氰酸根反应较M PU更彻底 ,而N PU的平均分子量远大于M PU。二体系反应的固化时间基本相同 ,且NB体系具有较好的初期流动性 ,将有利于临床操作。N PU与M PU材料分别呈现“C”型和反“S”型应力 应变特性 ,N PU的蠕变特性不太明显且硬度较小。两种材料的环境适用性基本相同。因而NB将可望取代传统的MB。Based on aliphatic alcohol, alcohol amine and amine, a new mixed expander (NB) for polyurethane prepolymer was prepared. This expander is very useful for rapid solidification medical polyurethane materials without carcinogenic ingredient. Taking a commercially available expander (MB), which is mainly composed of 4, 4'-methylene-bis (2-chloroaniline) (MOCA), as a reference, the reactions of the both expanders and polyether-based polyurethane prepolymer were traced by IR and GPC. Both systems showed similar solidification time, but the material based on NB, or N-PU, have a better initial fluidity, which is convenient for clinical operation. The reactive degree of isocyanate group higher in N-PU than in M-PU (material based on MB). The average molecular weight of N-PU is much higher than that of M-PU. The stress-strain curves of the material of N-PU and M-PU behaved like 'C' and reverse 'S' type respectively. N-PU does not show obvious creepin phenomenon and is less rigid. Environmental adaptability of both materials is the same. Therefore, NB is suggested to be a substitute for MB.

关 键 词：聚氨酯 扩链剂 栓堵剂 生物高分子 医用材料 

分 类 号：R318.08[医药卫生—生物医学工程]