零磁空间对金黄仓鼠脑中几种神经递质的影响  

Effect of Magnetic Free Field Space (MFFS) on GABA, Glycine and Taurine of Cortex,Cerebellum and Basilar Nucleus in Hamster

作　　者：李俊凤[1] 吴奇久[1] 王倩[1] 蒋锦昌[1] 金海强[2] 林云芳[2] 

机构地区：[1]中国科学院生物物理研究所 [2]国家地震局地球物理研究所,北京100081

出　　处：《生物化学与生物物理进展》2001年第3期358-361,共4页Progress In Biochemistry and Biophysics

基　　金：国家自然科学基金资助项目 (39770 1 96)&&

摘　　要：对饲养在近零磁空间 (MFFS)不同时间的金黄仓鼠大脑皮层、基底核和小脑中氨基酸类抑制性神经递质γ 氨基丁酸 (GABA)、甘氨酸 (glycine)及牛磺酸 (taurine)的含量进行了测定 .与正常地磁环境下饲养的动物相比 ,随着时间的推移 ,这几种递质在皮层中的含量变化不明显 ,在一个月后 ,基底核和小脑中GABA含量逐渐降低 ,而小脑中一个月后tau的含量却表现出逐渐升高的趋势 .这些递质的含量变化情况与某些神经疾病患者相应脑区这几种递质的变化表现出类似的规律 .The content of GABA, glycine and taurine in cortex, cerebellum and basilar nucleus of hamster living in the magnetic free field space was determined in different time. The change of three neurotransmitters is not distinct with the lapse of time in cortex. The GABA was decreased gradually in cerebellum and basilar nucleus and the taurine was increaced in cerebellum after a month. This change is similar with that of corresponding area in the brain of some kinds of neuropathes.

关 键 词：零磁空间 小脑 基底核 脑皮层 甘氨酸 牛磺酸 γ-氨基丁酸 仓鼠 神经递质 

分 类 号：R852.7[医药卫生—航空、航天与航海医学] Q693[医药卫生—临床医学]