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作 者:史明仪[1]
机构地区:[1]扬州大学医学院生理室,中国江苏扬州225001
出 处:《生命科学研究》2001年第2期173-176,共4页Life Science Research
基 金:the National Science Foundation of China (832 92 )
摘 要:运用在体细胞内电位记录法 ,观察了与肠系膜下神经节 ( IMG)相连的四组神经对 IMG神经元自发电位活动的影响 .结果显示扩张结肠或膀胱时 ,IMG细胞自发电位活动增加 ;切断或阻滞任一组神经均使 IMG细胞电位活动受抑 .其中结肠神经和腹下神经分别传导源自结肠尾段和膀胱等盆腔脏器的外周性兴奋 ,节间神经同时传导源自脊髓的中枢性和结肠的外周性兴奋 .肠系膜下神经节细胞的兴奋不仅源自脊髓 ,而且来源于结肠和膀胱 .定量研究表明后者比前者对神经节细胞兴奋的影响更大 .The excitable origin of guinea-pig inferior mesenteric ganglion (IMG) neurons in vivo was explored by a method with which intracellular recording of membrane potentials in IMG neurons in vivo was made. When the bladder or colon was inflated the spontaneous potential activities(SPA) of IMG neurons increased, while after blockade of anyone of the four groups of the nerves(FGN) connected to IMG respectively SPA of the cells reduced. This indicated that all of FGN set in excitatory inputs to IMG neurons. Colonic(CN) and hypogastric nerves (HN) convey peripheral excitatory inputs respectively from colon and bladder. Ascending mesenteric nerve(AMN) sends in both peripheral excitation from colon and central from the spinal cord. The excitation of IMG originates from not only the spinal cord as claimed traditionally, but also peripheral organs. The latter exerts stronger effect than the former.
分 类 号:R338.8[医药卫生—人体生理学]
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