妊娠合并肝功能损害对妊娠结局的影响  

Analysis of pregnancy with abnormal liver function

作　　者：狄文[1] 林其德[1] 方秀丽[1] 丁传伟[1] 孙贇[1] 

机构地区：[1]上海第二医科大学附属仁济医院妇科,200001

出　　处：《中国实用妇科与产科杂志》2001年第6期345-346,共2页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的　探讨妊娠合并肝功能损害 (妊娠肝损 )对妊娠结局的影响。方法　分析比较了 80例妊娠肝损患者及同期随机抽查的 5 6例非肝损患者 (对照组 )的临床资料。结果　肝损组新生儿体重、分娩孕周均显著低于对照组 (P <0 0 5 ) ;肝损组羊水污染率明显高于对照组 (P <0 0 5 ) ,肝损组新生儿窒息率高于对照组 ,但无统计学差异 ;肝损组血ALT >5 0 0nmoL·S-1/L患者与ALT <5 0 0nmoL·S-1/L的患者相比 ,早产儿发生率明显增加(P <0 0 5 )。结论　妊娠肝损可影响新生儿的体重 ,且羊水污染机会明显增加 。Objective To investigate the pregnancy outcome in women with hepatic dysfunction.Methods Retrospectively analyze the clinical data of 80 women with hepatic dysfunction in Aug.1990~Nov.2000 and 56 as control.Results The weight of newborn,days of pregnancy on women with hepatic dysfunction were significantly lower than those of the control group (P<0.05),and the rate of amniotic fluid stained by meconium were significantly different(P<0.05)too.But there was no significant difference about the newborn asphyxia(P>0.05).ALT>500nmoL·S -1 /L resulted in preterm delivery more frequently than that in ALT<500nmoL·S -1 /L(P<0.05)and the control group(P<0.001).Conclusion Pregnancy with hepatic dysfunction may affect the newborn weight and increase the possibility of the amniotic fluid stained.But under the intensive care and proper managements,the pregnant women with hepatic dysfunction can safely accomplish the pregnancy with a best quality of outcome.

关 键 词：妊娠合并症 肝功能损害 妊娠结局 

分 类 号：R714.255[医药卫生—妇产科学]