ICU呼吸机相关肺炎的流行病学调查及临床防治分析  

Epidemiology and prevention of ventilator-associated pneumonia in intensive care unit

作　　者：刘雪燕[1] 徐勇[2] 文舜康[1] 陈升汶[3] 

机构地区：[1]深圳市人民医院ICU科,深圳518020 [2]深圳市人民医院检验科,深圳518020 [3]深圳市人民医院呼吸科,深圳518020

出　　处：《中国实验诊断学》2001年第3期114-115,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的　了解呼吸机相关肺炎 (VAP)的病原菌及其药敏情况。方法　对深圳市人民医院ICU 46例VAP患者的痰培养及药敏结果进行回顾性分析。结果　本组VAP患者的细菌学培养 83 4%为G-杆菌 ,其中以铜绿假单胞菌、嗜麦芽假单胞菌和不动杆菌最为常见 ,药敏试验显示VAP对环丙沙星、丁胺卡那、氧哌嗪青霉素、特美汀及头胞他啶有较好的敏感性 ,而对依米配能的耐药性提高。结论　必须加强ICU机械通气患者下呼吸道细菌的检测 ,采取多种防治措施 。Objective\ To study the pathogenic bacteria and their antibiotics sensitivity of ventilator associated pneumonia(VAP) in intensive care unit. Methods The retrospective analysis was performed in the sputum cultures and antibiotics sensitivity results of 46 cases of VAP registered in ICU of Shenzhen People's Hospital. Results 83.4% of sputum culture Resutls were gram negative bacilli, most of which were Pseudomonas aeruginosa, Pseudomonas maltophilia and Acinetobacter. The cultures were highly sensitive to cirprofloxacin, kanamycin, piperacillin, Timentin and ceftazidime, but there was increased drug resistance of isolated bacteria to imipenem. Conclusions Mechanical ventilated patients in ICU must receive low respiratory tract bacteria monitor, and multiple prevention strategy shoud be adopted. Antibiotics should rationally be used according to the results of antimicrobial susceptibility tests during VAP therapy.

关 键 词：呼吸机相关肺炎 痰培养 药敏试验 ICU VAP 

分 类 号：R181.3[医药卫生—流行病学]