郑州市1992～1996年结核分支杆菌原发耐药性观察  

Primary drug resistance of Mycobacterium tuberculosis in Zhengzhou(1992～1996)

作　　者：陈裕 刘丽 吴宏君 李鸿昌 张华伟 王丽萍 刘万同 

机构地区：[1]郑州市结核病防治所,郑州45005

出　　处：《中国防痨杂志》2001年第3期181-183,共3页Chinese Journal of Antituberculosis

摘　　要：目的　了解郑州市 1992～ 1996年结核分支杆菌原发耐药性。方法　采用绝对浓度法进行6种抗结核药物的耐受性测定。结果　总原发耐药率、耐RFP率分别由 1992年的 4 1.5%、19.5%降至 1996年的 2 9.6 %、11.1%。结论　 1992～ 1996年郑州市结核分支杆菌原发耐药率和耐RFP率呈下降趋势。Objective To illustrate the primary drug resistance of M.tuberculosis in ZhengZhou,during 1992～1996. Methods Absolute concentration method was used for the detection of drug sensitivity of 6 antituberculosis agents. Results The rate of total primary drug resistance and resistance to rifampin decreased from 41.5%,19.5% in 1992 to 29.6%,11.1% in 1996,respectively. Conclusion The primary drug resistance of M.tuberculosis and to rifampin decreased in Zhengzhou,1992～1996.

关 键 词：结核分枝杆菌 药物耐受性 监测 抗结核药 

分 类 号：R446.5[医药卫生—诊断学]