三种替硝唑片剂的溶出度分析  

Dissolution of Three Kinds of Tinidazole Tablets

作　　者：郑晓娴[1] 金卫坤[1] 夏运岳[1] 

机构地区：[1]苏州大学附属第一医院药剂科,江苏苏州215006

出　　处：《镇江医学院学报》2001年第3期307-308,共2页Journal of Zhenjiang Medical College

摘　　要：目的 :考察三个厂家的替硝唑片的溶出度。方法 :以转篮法测定溶出 ,紫外分光光度法测定含量。结果 :三个厂家的替硝唑片的溶出均符合威布尔模型。结论 :三者的溶出参数TD,T30 ,T50 ,T80 及m均存在显著差异。Objective:To inspect the dissolutions of tinidazole tablets from three factories. Methods: The dissolution was performed in a ratating shaker. The content was determined by spectrophotometrical method. Results: The dissolutions of tinjdazole from the three factories accord with the Model of Weibubll. Conclusion:The main parameters of the three factories.T 30 , T D, T 50 , T 80 and m, have significant difference.

关 键 词：替硝唑 溶出度 紫外分光光度法 转篮法 

分 类 号：R978.61[医药卫生—药品]