绿海葵中的核苷类成分  

Nucleosides from Anthopleura stell

作　　者：禚如朋[1] 付宏征[1] 张礼和[1] 林文翰[1] 

机构地区：[1]北京大学天然药物及仿生药物国家重点实验室,北京100083

出　　处：《中草药》2001年第4期289-291,共3页Chinese Traditional and Herbal Drugs

摘　　要：目的　为了寻找抗肿瘤的活性成分。方法　利用溶剂法和色谱法对绿海葵进行了研究。结果　分离得到 5个核苷 ,经波谱学解析鉴定为 2 -羟基嘌呤核苷 ( ) ,脱氧肌苷 ( ) ,1-甲基黄嘌呤核苷 ( ) ,脱氧鸟苷 ( ) ,脱氧核糖胸腺嘧啶 ( )。结论　 为一新天然产物 ,其余均为海洋生物中首次发现。Object To study the chemical constituents of sea anemone, Anthopleura stell Verrill Methods The chemical constituents were isolated and purified by chromatographic methods and their structures elucidated by chemical evidences and spectra data Results 5 nucleosides were obtained and identified from the ethanolic extract as 2 hydroxy purine (Ⅰ); deoxyinosine (Ⅱ); 1 methylxanthosine (Ⅲ); deoxyguanosine (Ⅳ), and deoxyribo thymidine (Ⅴ) Conclusion Compound Ⅲ was a new natural product, while the others were found from sea anemone for the first time

关 键 词：绿海葵 核苷 1-甲基黄嘌呤核苷 成分 

分 类 号：R284.1[医药卫生—中药学]