糖尿病足患者微量白蛋白尿和糖尿病视网膜病变分析  

An Analysis of Microalbuminuria and Diabetic Retinopathy in Patients with Diabetic Foot

作　　者：宫雅南[1] 刘冬年[1] 朱沛庄[1] 熊玉冰[1] 黄伟文[1] 庄万江[1] 

机构地区：[1]广州医学院第二附属医院内分泌科,广州510260

出　　处：《广州医学院学报》2001年第2期51-53,共3页Academic Journal of Guangzhou Medical College

摘　　要：目的：探讨糖尿病足（ＤＦ）与微量白蛋自尿和糖尿病视网膜病变（ＤＲ）的关系。方法：对８７例 ２型糖尿病合并与不合并糖尿病足患者用放射免疫法（ＲＩＡ）进行２４ ｈ尿微量白蛋白的测定，并用眼底荧光造影进行糖尿病视网膜病变患病率分析。结果：ＤＦ组２４ ｈ尿微量白蛋白显著高于ＮＤＦ组（Ｐ＜０. ０５）。尿微量白蛋白与糖尿病足显著相关，ｒ＝０．２６４，Ｐ＜０．０５；ＤＦ组ＤＲ发生率显著高于ＮＤＦ组（Ｐ＜０．００１）。糖尿病视网膜病变与糖尿病足显著相关，ｒ＝０.４６２，Ｐ＜０.０１。结论：微量白蛋白尿和糖尿病视网膜病变与糖尿病足的发生显著相关，微血管病变参与了糖尿病足的发生。Objective: To explore the relationship between microalbuminuria and diabetic foot(DF)as well as the relationship between diabetic retinopathy (DR) and diabetic foot. Methods: The urine albumin was determined by RIA in 87 cases of type-2 diabetes with or without diabetic foot. The DR was diagnosed by using Fundus Fluorescence Angiography. Results: The level of urine albumim was significantly higher in the DF group than that in the NDF group(P＜0. 05). There was a close correlation between the level of urine albumin and diabetic foot(r=0. 264, P＜0. 05). The prevalence rate of DR was significantly higher in the DF group than that in the NDF group (P＜ 0.01 ). Diabetic retinopathy was closely related with diabetic foot, (r = 0.462, P＜ 0. 01 ). Conclusion: Microalbumiura and diabetic retinpathy have a strong relationship with diabetic foot. Microangiopathy play a role in the pathogenesis of diabetic foot.

关 键 词：糖尿病足 微量白蛋白尿 糖尿病视网膜病变 

分 类 号：R587.2[医药卫生—内分泌]