血栓闭塞性脉管炎血管中膜免疫复合物沉积的电镜观察  

Electron microscopic observation of immune complexes depositedin tunica media vasorum in patients with thromboangiitis obliterans

作　　者：崔新明[1] 陈越[2] 潘力[1] 崔丽[1] 李颖[1] 赵文光[3] 栗振宝[1] 

机构地区：[1]吉林大学基础医学院电镜室,吉林长春130021 [2]吉林大学基础医学院免疫教研室 [3]吉林大学中日联谊医院血管外科

出　　处：《白求恩医科大学学报》2001年第4期379-381,共3页Journal of Norman Bethune University of Medical Science

摘　　要：目的 :探讨血栓闭塞性脉管炎 (TAO)发病机制。方法 :利用透射电镜观察 9例 TAO患者血管中膜免疫复合物沉积与分布。结果 :在 4例 TAO患者血管中膜平滑肌细胞内和平滑肌细胞间观察到高电子致密度的免疫复合物沉积 ,同时还观察到与免疫复合物沉积与损伤相关的淋巴细胞、巨噬细胞、中性粒细胞。结论 :免疫复合物在血管壁沉积可能与Objective:To study the mechanism of thromboangiitis obliterans (TAO). Methods:The immune complexes deposited in tunica media vasorum of 9 patients with TAO were observed by transmission electron microscope. Results:The immune complexes deposited in smooth muscle cells and spaces between smooth muscle cells in tunica media vasorum of 4 patients with TAO were observed. Conclusion:Immune complexes deposited in vessels are closely related to the onset of TAO.

关 键 词：脉管炎 血栓闭塞性脉这炎 膜免疫复合物 电子显微术 TAO 

分 类 号：R654.4[医药卫生—外科学]