氦氖激光对人胚皮肤成纤维细胞诱发转化的研究  

Morphological transformation of human fetal skin fibroblasts induced by He-Ne laser in vitro

作　　者：张文庚[1] 徐刚[1] 

机构地区：[1]华西医科大学肿瘤研究所

出　　处：《激光杂志》1991年第2期85-88,共4页Laser Journal

基　　金：国家自然科学基金

摘　　要：本文首次报道用35mW氦氖激光辐照体外培养的人胚皮肤成纤维细胞,间日一次,每次10分钟,共15次,诱发了与致癌剂甲基硝基亚硝基胍相似的形态学转化。提示氦氖激光对人的体细胞可能具有潜在致癌性。This report, for the first time, demonstrates that He-Ne laser (35mW, 10min, once every other day, 15 times)irradiation, which was similar to carcinogen N-methyl-N-nitro-nitrosoguanidine, was able to induce the morphological transformation of human fetal skin fibroblasts in vitro. This result indicates He-No ]aser irradiation may have carcinogenic potential to human somatic cells.

关 键 词：激光 人体 胚胎 皮肤 纤维细胞 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]