^(31)PNMR研究水生动物细胞死亡过程的动力学性质  

Studies on the Kinetic Properties of Cells of Aquatic Animals During Death with ^(31)P NMR

作　　者：望天志[1] 杜菲[1] 毛希安[1] 

机构地区：[1]中国科学院武汉物理与数学研究所,波谱与原子分子物理国家重点实验室,武汉430071

出　　处：《高等学校化学学报》2001年第8期1388-1390,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学杰出青年基金 (批准号 :2 972 5 30 7);全国博士后科学基金资助

摘　　要：Cell death manner is related to the contents of intra cell energy substances. The rate constants and the half life time of ATP, phosphocreatine (PCr) and inorganic phosphorus (P i) in different cells of eel and crucian during their death have been determined with 31 P NMR. It has been found that there are differences in rate constants and change rule of these energy substances for different animals and different cells in the same animal from this study. The decreasing order of the half life time is: muscle of eel>brain of eel>muscle of crucian for ATP; brain of eel≈muscle of eel>muscle of crucian for PCr. These results are very vital to understanding the concerned change pattern of energy substances and the speed of cell death.Cell death manner is related to the contents of intra cell energy substances. The rate constants and the half life time of ATP, phosphocreatine (PCr) and inorganic phosphorus (P i) in different cells of eel and crucian during their death have been determined with 31 P NMR. It has been found that there are differences in rate constants and change rule of these energy substances for different animals and different cells in the same animal from this study. The decreasing order of the half life time is: muscle of eel>brain of eel>muscle of crucian for ATP; brain of eel≈muscle of eel>muscle of crucian for PCr. These results are very vital to understanding the concerned change pattern of energy substances and the speed of cell death.

关 键 词：细胞死亡 ATP 动力学 水生动物 能量代谢物质 磷31 核磁共振 变化规律 

分 类 号：Q255[生物学—细胞生物学] Q591.8