5-(2-羟基苯基)-10,15,20-三苯基卟啉及其衍生物的新法合成  

New methods for the synthesis of 5-(2-hydroxyphenyl) -10,15,20-triphenylporphyrin and its derivatives

作　　者：何宏山[1] 钟丽[2] 林岩心[1] 黄理耀[1] 

机构地区：[1]华侨大学化工学院,泉州362011 [2]华侨大学医院,泉州362011

出　　处：《化学试剂》2001年第3期169-170,172,共3页Chemical Reagents

基　　金：福建省自然科学基金 (D0 0 1 0 0 0 9)

摘　　要：在二甲苯溶液中 ,以氯乙酸作催化剂 ,在 1 3 2℃及常压下合成了 5-(2 -羟基苯基 ) -1 0 ,1 5,2 0 -三苯基卟啉等 3种不对称卟啉。产物经红外光谱、紫外可见光谱等进行了表征。研究了反应时间、反应物比例、温度、浓度等对收率的影响 ,在优选的反应条件下 ,产物收率可达 6.3 %。Three unsymmetrical tetraphenylporphyrins 5 (2 hydroxyphenyl) 10,15,20 tri(R)porphyrins,where R=phenyl,2 methoxylphenyl and 4 methylphenyl,were prepared by the condensation of pyrrol with two different aldehydes in the presence of chloroacetic acid in xylene solvent.The yield was 6.3%,which was higher than Litter′s method.The factors which influence the yields of the porphyrins were investigated.

关 键 词：不对称卟啉 合成 5-(2-羟基苯基)-10 15 20-三苯基卟啉 衍生物 光谱 表征 

分 类 号：O626.13[理学—有机化学]