重症急性胰腺炎的早期肠内营养支持  

The effect of early enteral nutrition support for the patients with severe acute pancreatitis

作　　者：谌章庆[1] 邹声泉[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院普外科,武汉430030

出　　处：《临床外科杂志》2001年第4期217-219,共3页Journal of Clinical Surgery

摘　　要：目的　研究早期肠内营养支持对重症急性胰腺炎的治疗作用。方法　将 5 0例经证实为重症急性胰腺炎的病人随机分为两组 ,PN组 (2 5例 )和EN组 (2 5例 )。PN组行TPN支持 ,EN组从入院第 1天起经螺旋鼻饲管 (放置于Treitz韧带下 )或术后经空肠饲养管输注能全力 ,能量12 5kJ/kg·d ,氮入量 0 .2 /kg·d。 结果　入院后 1～ 4d患者血清PA、RBP浓度较正常水平有明显下降 (P <0 .0 5 ,P <0 .0 1) ,经 14d的EN和PN支持后基本恢复到以前水平。EN的营养恢复作用与PN相比无明显差异。经 14d的营养支持 ,EN组的感染率明显低于PN组。结论　营养支持治疗可以改善重症急性胰腺炎患者的营养状况 。Objective To elucidate the effect of early enteral nutrition support(ENS) for the patients with severe acute pancreatitis(SAP).Methods Fifty patients with SAP were at random divided into two groups: enteral nutrition group(EN group, 25 cases), parenteral nutrition group(PN group, 25cases). PN group was given total parenteral nutrition(TPN),125 kJ/(kg·d) of energy, nitrogen intake:0.20g/(kg·d). In EN group, the naso intestinal tube was placed posterior to ligament Treitz. Since the 1st day nutrilion was infused.Results On the first?4th day, the serum RBP?PA levels were obviously decreased (P<0.01,P<0.05);and all returned to normal levels after 14 days.ENS help to improve nutritional status of SAP patients and were not significant different from PN groap. The number of infection of the patients with SAP was significanly lower in EN group than in PN group.Conclusion Nutrition supports help to ameliorate the nutritional status of the patients with severe acute pancreatitis and the early enteral nutrition support is rational and adequate in the treatment for the patients with SAP.

关 键 词：重症急性胰腺炎 治疗 肠内营养 肠外营养 

分 类 号：R657.51[医药卫生—外科学]