盐酸氨溴索可减少心内直视手术后肺不张  

Cyclohexanol Hydrochloride Can Reduce Atelectasis after Heart Operation

作　　者：唐白云[1] 陈光献[1] 张希[1] 熊迈[1] 陈振光[1] 姚尖平[1] 童萃文[1] 

机构地区：[1]中山医科大学附属第一医院心胸外科,广东广州510080

出　　处：《中山医科大学学报》2001年第4期286-288,共3页Academic Journal of Sun Yat-sen University of Medical Sciences

摘　　要：【目的】观察盐酸氨溴索 (沐舒痰 )减少心内直视术后呼吸道并发症的作用。【方法】 10 0例心内直视术后患者 ,随机分为实验组和对照组各 5 0例 ,实验组术后开始静脉应用盐酸氨溴索 ,对照组应用LP(陈皮、茴香、远志、吐温的合剂 )。观察比较两组患者术后 3～ 14d咳痰困难程度、痰液粘稠度、排痰难度、肺部罗音、呼吸系统并发症及副作用。【结果】实验组痰液粘稠度、排痰难度、肺部罗音明显低于对照组 (14% ,P<0 0 5 ) ,肺不张发生率为 4% ,明显低于对照组 (14% ,P <0 0 5 ) ,两组均未见明显副作用。【结论】盐酸氨溴索应用于心内直视术后可显著减少肺不张并发症。Objective To observe the effects of cyclohexanol hydrochloride (Mucosolvan) on reducing respiratory complications after heart operations. Methods One hundred patients were randomly divided into the studied and control group. Each group consisted of fifty patients. Cyclohexanol hydrochloride was infused intravenously in the studied group and LP (the mixture of ChenPi, HuiXiang, YuanZhi and AnYuan) were used in the control group. 3～14 d after heart operations, density of phlegm, difficulty in expectoration, pneumonic rales, respiratory complications and side effects of drugs were observed and compared. Results The prevalence of high density of phlegm, difficulty in expectoration and pneumonic rales were markedly less in the studied group than in the control (P<0.05). The prevalence of atelectasis in the studied group was 4%, much lower than that in the control group(14%, P<0.05). No obvious side effects were found in the two groups. Conclusions Administration of cyclohexanol hydrochloride in patients after heart operations can reduce the respiratory complications, especially atelectasis.

关 键 词：盐酸氨溴索 心内直视手术 术后 肺不张 预防 

分 类 号：R654.2[医药卫生—外科学]