电针内关穴诱导大鼠延髓原癌基因c-fos表达  

Effect of Electro-acupuncture of Neiguan Point on Proto-oncogene c-fos Expression in Rat Medulla Oblongata

作　　者：张进[1] 陈东风[1] 李伊为[1] 沈逸萍[1] 徐勤[2] 

机构地区：[1]广州中医药大学解剖教研室,广州510405 [2]广州中医药大学病理教研室,广州510405

出　　处：《广州中医药大学学报》2001年第2期134-136,共3页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广州中医药大学科研基金!(N0 .XJ980 0 9)

摘　　要：【目的】观察电针内关穴诱导大鼠延髓内的原癌基因c -fos表达及分布特点。【方法】采用抗FOS蛋白的免疫组织化学方法。【结果】电针内关穴可引起大鼠延髓内神经元的广泛c -fos表达 ,其FOS样免疫反应 (FOS -like -immunoreactivity ,FLI)阳性神经元广泛分布于延髓的孤束核、迷走神经背核、下橄榄核、楔束核、楔束外核、腹外侧网状核、疑核 ,网状结构中也散在分布着FLI神经元如网状巨细胞核等。【结论】提示电针“内关”穴激活了上肢的本体觉传导路 ,并且激活了延髓内与内脏信息相关的中枢核团。Objective To examine the proto_oncoge ne c_f os expression and its distribution in rat medulla oblongata induced by electro_a cupuncture of Neiguan point. Methods Anti_c_fos immunohistochemical method w as applied. Results Fos_like immunoreactive positive neurons mainly located in nucleus tractus solitarius, dorsal motor nucleus of vagus nerve, inferior ol ive nucleus, cuneate nucleus, external cuneate nucleus, and ventrolateral m edulla(VLM). VLM included lateral reticular nucleus, ambiguous nucleus and the s urrou nding reticular structure. Conclusion Electro_acupuncture of Neiguan point c an activate the proprioceptive pathways and the nucleus in the medulla oblongata that is related to visceral informatio n.

关 键 词：内关穴 延髓 针灸效应 原癌基因 c-fos 电针 

分 类 号：R245.97[医药卫生—针灸推拿学]