心疾宁胶囊对心率变异性和QT离散度的影响  

Influence of “Xinjining Capsule” on Heart Rate Variability and QT Dispersion

作　　者：薛金贵[1] 林慧娟[2] 张宁宁[2] 尹承娥[2] 

机构地区：[1]上海中医药大学,上海200032 [2]山东中医药大学附属医院,山东济南250011

出　　处：《上海中医药杂志》2001年第5期24-26,共3页Shanghai Journal of Traditional Chinese Medicine

摘　　要：为观察心疾宁胶囊对室性心律失常患者心率变异性 (HRV)和QT离散度 (QTd)的影响 ,将 45例室性心律失常患者随机分为心疾宁治疗组 (2 5例 )和心得安对照组 (2 0例 ) ,治疗 1个月后观察疗效。结果 :治疗前后治疗组 2 4小时时域各指标均有显著性改变 (P <0 .0 1 ) ;夜间各指标治疗组显著改变 (P <0 .0 5 ) ,优于对照组 ;两组白天SDNN和Tri Ind均显著改变 (P <0 .0 5 ) ;治疗组LF、HF、LF/HF显著改变 (P <0 .0 1 ) ,对照组LF、HF、LF/HF显著改变 (P <0 .0 5 ) ;治疗组QTd、QTcd显著改变 (P <0 .0 1 ) ,对照组QTd显著改变 (P <0 .0 1 ) ,QTcd显著改变 (P <0 .0 5 )。提示心疾宁胶囊能提高心率变异性 ,降低QT离散度。To observe the influence of“Xinjining Capsule”on heart rate variability(HRV)and QT dispersion(QTd)in patients with ventricular arrhythmia,45 cases were randomly classified into treatment group(25 cases treated by“Xinjining Capsule”)and control group(20 cases treated by propanolol).1 month treatment later,24 hour time domain indexes SDNN and Tri Ind in treatment group changed obviously( P <0.01);night indexes in treatment group changed significantly( P <0.05),better than those in control group;day indexes in two groups changed remarkably( P <0.05);in treatment group,LF,HF,LF/HF,QTd and QTcd changed markedly( P <0.05);in control group,LF,HF,LF/HF,QTd and QTcd changed significantly( P <0.01～0 05).

关 键 词：心疾宁胶囊 心率变异性 QT离散度 室性心律失常 中医药治疗 

分 类 号：R259.417[医药卫生—中西医结合] R540.41[医药卫生—中医内科学]