山西省疑似流行性乙型脑炎病例血清学检测分析  

Analysis on Serological Detection of Suspected Japanese Encephalitis Cases in Shanxi Province

作　　者：赵习芳[1] 邵文爱[1] 那丹宇[1] 郑雷[1] 聂小勇[1] 

机构地区：[1]山西省卫生防疫站,太原030012

出　　处：《中国计划免疫》2001年第3期149-151,共3页Chinese Journal of Vaccines and Immunization

摘　　要：为了解山西省流行性乙型脑炎 (乙脑 )的流行状况 ,对该省 1994～ 1999年的乙脑疫情报告和血清学诊断病例做了分析。对 1994、1998年该省乙脑两个高峰期的疑似乙脑病人的血清 ,采用反向被动血凝抑制试验检测了血清特异性抗体和IgM抗体。结果显示 :1994～ 1999年共报告乙脑病例 1796例 ,绝大多数是经临床诊断的 ,经实验室检测的仅 399例 ,占 2 2 2 % (399/ 1796 ) ,确诊 188例 ,10 5 % (188/ 1796 )。 1994、1998年 2 31例疑似乙脑病人 ,经血清学确诊 115例为乙脑 (4 9 8% )。此 115例分布在该省 9个地区 (市 ) ,>40岁中老年人占 5 0 %以上。中老年人接种乙脑疫苗 ,对降低乙脑发病率十分必要。In order to understand the epidemic situation of Japanese encephalitis (JE) in Shanxi Province, we made analysis on JE case reporting and serological testing of the patients in the time of 1994～1999. The patients occurred during the two JE epidemic peaks in 1994 and 1998 were tested for JE specific antibody and IgM antibody by the method of PRHI. The results showed that 1796 JE cases reported in 1994～1999 were mostly clinically diagnosed, only 399 cases of them were laboratory tested that accounted for 22.2% (399/1*!796), the laboratory identified cases were 118, accounting for 10.5% (118/1*!796). 115 of 231 suspected JE patients occurring during the two JE epidemic peaks were serologically confirmed to be JE patients, they distributed in 9 prefectures and cities of the province and among them people of middle-and-old age accounted for more than 50%. So, it is necessary to vaccinate these people to make the JE incidence decrease.

关 键 词：流行性乙型脑炎 IGM抗体 反向被动血凝抑制试验 

分 类 号：R512.32[医药卫生—内科学]