山东肿足蕨化学成分研究(Ⅵ)肿足蕨碱的分离和鉴定  

STUDIES ON CHEMICAL COMPOSITION OF HYPODEMATIUM SINENSE IWATSUKI(Ⅵ)

作　　者：陈亚民[1] 王宁[1] 卢英华[1] 陈雁君[1] 马存升 

机构地区：[1]济宁医学院化学教研室

出　　处：《济宁医学院学报》1991年第2期10-12,共3页Journal of Jining Medical University

摘　　要：从金星蕨科植物山东肿足蕨(Hypodematium Sinense Iwatsuki)的全草分得一种新化合物,通过紫外光谱、红外光谱、高分辨质谱和二维核磁共振新技术确定其结构是一种具有苯基取代苯并氮杂环辛四烯新型骨架的生物碱,命名为肿足蕨碱(Hypodematine),又用原子吸收分光光度法和荧光分光光度法测定了该生药中有重要生理功能的硒、铬、钴,镍4种微量元素的含量。A novel alkaloid,named Hypodematine,has been isolated from Hypodematium Sinense Iwatsuki (belonging to Thelypterdanceae).Its structure has been elucidated to be of a novel skeleton of benzo-aza-cyclooctatetraene with a phenyl substitution by means of the (IR,UV,MS,~1H-,^(13)C-and 2D-NMR) spe- ctroscopy.Moreover,the fact that it contains four indispensable trace elements (Se,Cr,Co,Ni)in the crude drug has been determined by Atomic Absorption Spectrometry and Fluorescence Spectrometry.

关 键 词：山东肿足蕨 肿足蕨碱 分离 鉴定 

分 类 号：R931.6[医药卫生—生药学]