窄叶大黄蒽醌类化学成分研究  

Studies on anthraquinone constituents in Rheum sublanceolatum

作　　者：向兰[1] 郑俊华[1] 果德安[1] 寇晋萍 范国强 段豫萍 秦晨 

机构地区：[1]北京大学药学院生药学生物技术室,北京100083 [2]北京市中药科学研究所,北京100011

出　　处：《中草药》2001年第5期395-397,共3页Chinese Traditional and Herbal Drugs

摘　　要：目的　对窄叶大黄根及根茎的化学成分进行研究。方法　采用硅胶柱层析进行分离 ,通过化学和波谱分析方法鉴定化合物结构。结果　分离得到 6个蒽酯类化合物 ,分别鉴定为大黄酚 (chrysophanol, )、大黄素甲醚(physcion, )、大黄素 (emodin, )、大黄素 - 8- O- β- D-吡喃葡萄糖苷 (emodin- 8- O- β- D- glucopyranoside, )、芦荟大黄素 - 8- O- β- D-吡喃葡萄糖苷 (aloe- em odin- 8- O- β- D- glucopyranoside, )和 ω-羟基大黄素 (citreorosein, )。Object To study the anthraquinone constituents in rhizoma and radix of Rheum sublanceolatum C Y Cheng et T C Kao Methods The constituents were isolated through column chromatography, and their structures elucidated through physicochemical and spectral analysis Results 6 anthraquinones were isolated and identified as chrysophanol (Ⅰ); physcion (Ⅱ); emodin (Ⅲ); emodin 8 O β D glucopyranoside (Ⅳ); aloe emodin 8 O β D glucopyranoside (Ⅴ) and citreorosein (Ⅵ) Conclusion All these compounds were isolated from R sublanceolatum for the first time

关 键 词：蓼科 大黄属 窄叶大黄 蒽酯类 化学成分 中药 

分 类 号：R284.1[医药卫生—中药学]