朴实颗粒剂的制剂学研究  

STUDY ON PHARMACEUTICS OF PUSHI GRANULES

作　　者：孙毅毅[1] 侯世祥[1] 刘君 杨远明 

机构地区：[1]四川大学华西药学院,四川成都610041 [2]四川省邮电医院,四川成都610041 [3]四川圣科药业有限责任公司,四川绵阳621000

出　　处：《华西药学杂志》2001年第3期188-190,共3页West China Journal of Pharmaceutical Sciences

摘　　要：目的：对朴实汤剂的剂型改进。方法：通过溶剂选择和正交设计筛选合理的提取工艺，并制订质量控制方法。结果：提取工艺为６倍５０ ％乙醇加热回流２次，每次１．５ｈ。结论：提取工艺合理，质量控制较为全面，奠定了较好的临床前药学研究基础。OBJECTIVE: To study the pharmaceutics in re- formation of Pushi decoction. METHODS: To establish the qual- ity control methods and optimize the extractive process by or- thogonal design. RESULTS: The optimum extraction condition was that adding six times amount of 50% alcohol as solution, stotally refluxing for 2 times, 1.5 h at each time. The methods, which of determining content of main ingredients and identifica- tions of other three Chinese materia medica by TLC, were in- vestigated. CONCLUSION: The tachnologieal process was suit for preparation of Pushi granules.

关 键 词：朴实颗粒剂 制备工艺 质量控制 制剂学 

分 类 号：R283.627[医药卫生—中药学]