遗传因素对驻疆部队指战员血压的影响  

Effects of Hypertension Genetic Factors on Arterial Blood Pressure of Soilders and Officers Served in Xinjiang

作　　者：李志玫[1] 廖禹林[1] 梁兰青[1] 苏伟[1] 席丽丽[1] 张凤英[1] 王小丽[1] 贾世纯[1] 

机构地区：[1]解放军兰州军区乌鲁木齐总医院心肾内科,新疆乌鲁木齐830000

出　　处：《临床军医杂志》2001年第2期21-23,共3页Clinical Journal of Medical Officers

摘　　要：目的　了解高血压家族史对部队官兵血压的影响程度及与高血压患病率的关系。方法　采用问卷调查及体格检查的方法对驻疆某部 3 190人进行了现场调查。调查对象均为男性 ,平均年龄 (2 0 .9± 3 .0 )岁 ,服役年限平均 (2 .9± 2 .8)年。结果　与无家族史者相比 ,有高血压家族史者其收缩压和舒张压水平显著增加 (P <0 .0 0 1) ,增幅平均达 2 .6 / 2 .0mmHg ,且高血压的患病粗率也显著增加 (5 .84%对 3 .0 7% ,上升 47% ) ;双亲血压均高对子女血压的影响大于单亲血压高者 ,高血压的患病率增高 ;而父亲血压增高比母亲血压增高对子女的血压影响更大 ,且高血压的患病率明显增加。经年龄及体重校正后仍显示有高血压家族史者 ,其血压水平及高血压患病率较无家族史者呈显著上升趋势。结论　高血压家族史不但影响部队官兵的血压水平 ,而且明显增加高血压患病的危险性 ,表明遗传因素在高血压的发病中起着重要的作用。Objective To study the effects of familial arterial hypertension on the level of arterial blood pressure and prevalence of hypertension in armymen. Method A cross-section study was performed in Xinjiang including 3 190 men aged 20.8±3.0 years. Systolic and diastolic pressures were measured using WHO recommendations. Result Subjects with familial hypertension have significant higher arterial pressure (2.6/2.0 mmHg, P<0.001) and a higher prevalence rate of hypertension than those with normotensive parents (5.84% vs 3.07%, P<0.05). When both parents were hypertensive, the difference was more pronounced that those with normotensive parents. Hypertension was more frequent in subjects with a hypertensive father than those with a hypertensive mother. After adjusted for the age and body mass index, armymen with familial hypertension still showed a significant higher prevalence of hypertension and level of arterial pressure than the men without familial hypertension. Conclusion The level of blood pressure in young armymen is related to the family history of hypertension which is a strong predictor of hypertension.

关 键 词：高血压 流行病学 遗传因素 部队 

分 类 号：R544.1[医药卫生—心血管疾病]