虎杖对小鼠CCl_4性肝损伤的保护作用  

Protection of Huzhangjianji to liver injury caused by carbon tetrachloride

作　　者：刘蕾[1] 李丽[2] 张蕊[3] 谭宏[2] 王淑湘[1] 

机构地区：[1]佳木斯大学基础医学院 [2]佳木斯大学口腔医学院 [3]佳木斯大学图书馆

出　　处：《黑龙江医药科学》2001年第3期20-21,共2页Heilongjiang Medicine and Pharmacy

摘　　要：观察虎杖煎剂对肝损伤的保护作用，采用以CCl4(四氯化碳)致小鼠肝损伤为模型，观察虎杖煎剂对小鼠肝脏损伤血清及肝脏有关指标的变化，结果表明虎杖煎剂能明显的降低CCl4诱导的肝损伤小鼠血清ALT、AST值升高，增强肝细胞SOD活力，降低MDA含量，说明虎杖煎剂对CCl4致肝损伤具有一定保护作用。Objective: To observe the protection of Huzhangjianji to mice liver injury caused by CCl4. Methods: We established the animal model of mice injury caused by CCl4. and measured the AST, ALT and MDA content in mice serum and the activity of SOD in mice lives cell were tested. Results: Huzhangjianji had significant effect on protecting mice injury caused by CCl4.

关 键 词：虎杖煎剂 肝损伤 CCL4 小鼠 保护作用 实验研究 

分 类 号：R285.5[医药卫生—中药学]