应用复合型神经桥接体修复周围神经缺损的临床研究  

Clinic Study on the Application of Compound Nerve Bridging for Repair of Peripheral Nerve Defect

作　　者：张朝跃[1] 詹瑞森[1] 吴松[1] 赵自平[1] 江皓[1] 王剑龙[1] 杨檑[1] 

机构地区：[1]中南大学湘雅三医院,中国湖南长沙410013

出　　处：《湖南医学》2001年第4期249-251,共3页Hunan Medical Journal

基　　金：湖南省卫生厅科研基金资助项目 (编号 0 0 0 61 )

摘　　要：目的研究修复周围神经缺损新的手术方法。方法应用植入自体雪旺细胞的胎儿神经复合型神经桥接体 ,修复周围神经缺损 42例 ( 5 7条 ) ,术后 1年进行神经功能评定。结果本组42例 ,得到随访 38例 ,随访时间 12～ 36个月 ;按Seddon的周围神经损伤术后恢复评定标准进行评定 ,优良率为 69.0 5 %。结论植入自体雪旺细胞的胎儿神经复合型神经桥接体移植 ,是一种修复周围神经缺损的新方法 ,具有进一步深入研究和临床应用的前景。ObjectiveTo study a new operative method of repairing the peripheral nerve defect. MethodsThe compound nerve bridging was made by grafting autogenous Schwann cells into fetus nerves.It was applied to repair defects of 57 peripheral nerves in 42 patiants Evaluation of nerve function was performed one year after operation. ResultsThirty-eight out of 42 cases were followed up from 12 to 36 months. According to Seddon's functional assessment criterion for postoperative recovery of peripheral nerve,the rate of excellent and good results after treatment was 69.05 %. ConclusionsThe compound nerve bridging made by grafting Schwann cells into fetus nerve is a new method for repair of peripheral nerve defect and would bring forth prospects of intensive study and clinical application.

关 键 词：复合型神经桥接体 周围神经损伤 周围神经 神经移植 修复 

分 类 号：R651.3[医药卫生—外科学] R622.3[医药卫生—临床医学]