黄芩苷对眼科常见病原菌的体外抗菌作用  

Studies on in vitro antibacterial action of baicalin in vitro

作　　者：程国强[1] 冯年平[2] 唐琦文 李蕾[4] 

机构地区：[1]上海中医药大学微生物学教研室,上海200032 [2]上海中医药大学药学院,上海200032 [3]上海市眼病中心防治所,上海200040 [4]复旦大学医学院附属眼鼻耳科医院,上海200031

出　　处：《中国医院药学杂志》2001年第6期347-348,共2页Chinese Journal of Hospital Pharmacy

摘　　要：目的：探讨黄芩苷的体外抗菌作用。方法：以临床眼科常见病原菌为受试菌，采用连续倍比稀释法，观察黄芩苷的最低抑菌浓度和最低杀菌浓度。结果：黄芩苷的最低抑菌浓度和最低杀菌浓度分别为40～640倍及20～1280 倍。结论：黄芩苷对所有受试菌均有不同程度的抑菌和杀菌作用，且抗菌谱广， 抗菌作用强。：OBJECTIVE To study the in vitro antibacterial;acti on of baicalin in vitro. METHODS Using the test-bacterial isolated from clinic,minimal i nbibitory concentration (MIC) and minimal bactercidal concentration (MBC) of bai calin were observed. RESULTS MIC and MBC of baicalin were 40～640 times and 20～1280 times,respectively.CONCLUSIONS Baicalin was inhibitory drug an d bactericide on all test-bacterical in different extent,its antibacterial spec trum was wide,the anti-bacterial potency was high .

关 键 词：黄芩苷 抗菌作用 眼科 病原菌 中药 

分 类 号：R285.5[医药卫生—中药学]