心力衰竭时的炎性介质  

Inflammatory mediators in heart failure .

作　　者：张福春[1] Josef Niebauer Jiangtao Yu 郭静萱[3] 

机构地区：[1]北京大学第三医院 [2]Heart center,University of Leipzig.Russenstrasse 19,04289.Leipzig Germany [3]北京大学第三医院心内科,北京,100083

出　　处：《中国心血管杂志》2001年第4期229-231,共3页Chinese Journal of Cardiovascular Medicine

摘　　要：细胞毒因子已被认为在心力衰竭病人的功能状态和发病机制中起主要的作用。本文复习了正在进行的有关抗细胞毒因子 治疗效果的系列研究,这些治疗直接针对肠中细胞易位过程和内毒索本身,即细菌内毒索与免疫活性细胞的结合位点,或两者兼 之。Cytokines have been identified as a major player in the pathogensis and the funtiond status of patients with heart failure. Herein we review studies which are under way to assess the effects of anti-cytokine therapy, where soon we may see treatments directed against bacteria in the bowel,the translocation process,and endotoxin itself,the binding sites of bacteral endotoxin on immune competent cells,or both.

关 键 词：细胞毒因子 心力衰竭 抗细胞毒因子治疗 炎性介质 

分 类 号：R541.6[医药卫生—心血管疾病]