光量子血液疗法对血小板的影响  

Effects of ultraviolet irradiation on platelet

作　　者：栾建凤[1] 朱培元[1] 雷千红[1] 万柏珍[1] 叶东[1] 

机构地区：[1]南京军区南京总医院输血科,南京210002

出　　处：《临床检验杂志》2001年第3期157-158,共2页Chinese Journal of Clinical Laboratory Science

摘　　要：目的　探讨光量子血液疗法对血小板的影响。方法　血液光量子前后进行血小板计数和血浆α颗粒膜蛋白 140 (GMP 140 )测定 ,并对光量子前后的血小板形态进行电镜观察。结果　与光量子化前相比 ,量子化后 ,血液的血小板数有所下降 (P<0 .0 5 ) ,血浆中的GMP 140含量显著升高 (P <0 .0 1) ,电镜结果显示量子化后血小板伪足形成增多 ,并伴有血小板碎片。结论　在本试验条件下紫外线照射对血液中的血小板有激活和形态损害作用。Objective\ To explore the effects of ultraviolet irradiation on platelet. Methods \ Three assays were been developed.These include platelet count,release of alpha granule membrane protein 140(GMP 140)and morphology of platelet by electron micrograph in those samples before and after ultraviolet irradiation.Results\ Compared with the nonirradiated controls,the irradiated units showed significant changes including decrease of platelet count,increase of release of GMP 140 and platelet lesion in morphology.Conclusion\ Ultraviolet irradiation may have activation and lesion effect in platelet.

关 键 词：光量子血液疗法 紫外线照射 血小板计数 Α颗粒膜蛋白-140 电镜 

分 类 号：R457[医药卫生—治疗学] R446.111[医药卫生—临床医学]