慢性肾炎患者心率变异性改变  

Changs of Heart Rate Variability in Patients with Chronic Nephritis

作　　者：陈伊伦[1] 胡申江[1] 陈宝仙[1] 赵力[1] 

机构地区：[1]浙江大学医学院附属第一医院,浙江杭州310003

出　　处：《浙江大学学报（医学版）》2001年第4期167-169,共3页Journal of Zhejiang University(Medical Sciences)

基　　金：浙江省卫生厅科研基金资助项目

摘　　要：目的 :通过心率变异性测定以了解慢性肾炎患者自主神经功能状态 ,并探讨其机理和临床意义。方法 :对 2 0名正常人 ,40名肾功能正常期、1 8名肾功能不全代偿期、2 1名肾功能不全失代偿期、1 9名肾功能衰竭期和 1 4名尿毒症期的慢性肾炎患者 ,进行了心率变异性测定。心率变异性以SDNN、SDANNindex、SDNNindex和 r MSSD作为观察指标。结果 :慢性肾炎患者随着肾功能损害程度的加重 ,SDNN、SDANNindex、SDNNindex、r MSSD逐渐降低。结论 :慢性肾炎患者随着肾功能的减退 ,心率变异性下降 ,自主神经调节功能下降 。Objective: To explore the function of autonomic nerves by measurement of heart rate variability in patients with chronic nephritis. Methods: Heart rate variability was detected in 20 normal controls,40 patients of normal renal functions, 18 patients of compensatory renal functions, 21 patients of decompensated renal functions, 19 patients of renal failure and 14 patients of uraemia and the patients all had chronic nephritis.The heart rate variability indices of SDNN,SDANNindex,SDNNindex and rMSSD were used. Results: SDNN,SDANNindex,SDNNindex and rMSSD descended with the worsening damage of the renal functions in the patients with chronic nephritis. Conclusion: The decrease of heart rate variability and the abnormality in regulation function of autonomic nervous become more serious with the worsening damage of the renal functions in chronic nephritis,which is important in heart events.

关 键 词：慢性肾功能衰竭 慢性肾炎 心率变异性 

分 类 号：R692.3[医药卫生—泌尿科学] R692.5[医药卫生—外科学]