细胞内转导肽——开启细胞调控之门的钥匙  

Intracellular transduction peptide: a key for the study of cell regulation

作　　者：马大龙[1] 

机构地区：[1]北京大学人类疾病基因研究中心,北京100083

出　　处：《北京大学学报（医学版）》2001年第4期292-294,共3页Journal of Peking University:Health Sciences

基　　金：国家重点基础研究发展规划项目 (973)基金 (G2 0 0 0 0 5 6 90 9)资助&&

摘　　要：To establish and develop an efficient import system for bio molecules into cells and nucleus is important for the study of signal transduction as well as therapeutic application. A number of peptides have been found to be able to deliver bio molecules, including proteins, DNAs, and oligonucleotides, into mammalian cells, which are known as transduction peptide or protein transduction domain (PTD). This review gives a brinef introduction to the structures, functions and application of the transduction peptides.To establish and develop an efficient import system for bio molecules into cells and nucleus is important for the study of signal transduction as well as therapeutic application. A number of peptides have been found to be able to deliver bio molecules, including proteins, DNAs, and oligonucleotides, into mammalian cells, which are known as transduction peptide or protein transduction domain (PTD). This review gives a brinef introduction to the structures, functions and application of the transduction peptides.

关 键 词：蛋白质转导 肽类 导入系统 细胞内转导肽 

分 类 号：Q25[生物学—细胞生物学]