唾液酯酶多态性在个体识别中的应用研究  

A study on polymorphism of salivary esterase in personal identification

作　　者：樊爱英[1] 昝玉玺[2] 刘红军[1] 高革[3] 张金莲[3] 

机构地区：[1]新乡医学院法医教研室,河南453003 [2]新乡医学院生物化学教研室,河南453003 [3]新乡医学院分析测试实验室,河南453003

出　　处：《法医学杂志》2001年第3期155-156,共2页Journal of Forensic Medicine

摘　　要：目的 探讨唾液酯酶（ Set）多态性在法医学亲权鉴定和个体识别方面的应用价值。方法 应用聚丙烯酰胺凝胶盘状电泳及固蓝 RR染色方法，调查了 114名中国人 Set的表型分布及基因频率，用χ 2检验进行统计学分析。结果 中国人酯酶表型频率 Set F 22.81％， Set FS 50.88％， Set S 26.31％ ;基因频率为 SetF 0.482 5， SetS 0.517 5;非父排除机率为 0.187 5，个体识别率为 0.619 9。结论 Set有较高的父权排除率和个体识别率，可作为法医学亲权鉴定和个体识别的重要标记系统之一。Objective To research the value of polymorphism of salivary esterase(Set)in paternity and personal identification. Methods Phenotype and genotype of human salivary esterase were detected in 114 liquid saliva samples from the Chinese population by disc electrophoresis and fast blue RR staining assay. Results The frequency of Set type was F 22.81％ ,FS 50.88％ ,S 26.31％ .The estimated gene frequency of Set F was 0.482 5 and SetS was 0.517 5.The PE was 0.187 5 and the DP was 0.619 9.Conclusion Polymorphism of salivary esterase (Set) was practical in paternity and personal identification.

关 键 词：唾液酯酶 基因频率 亲权鉴定 个体识别 

分 类 号：D919.4[医药卫生—法医学]