中西药联合防治急性心肌梗死溶栓再灌注心律失常的临床研究  

Studies on preventive and therapeutic effects of traditional Chinese medicine combined with western medicine on cardiac arrhythmia induced by reperfusion injury in patients with acute myocardial infarction

作　　者：许荣廷[1] 王涓冬[1] 邢介玲[1] 隋文娟[1] 

机构地区：[1]山东大学第二医院急症科,山东济南250033

出　　处：《中国中西医结合急救杂志》2001年第3期166-168,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：山东省中医管理局科研基金资助项目!( No.19992 8)

摘　　要：目的 :探讨早期应用中药针剂葛根素和脉安定防治急性心肌梗死 (AMI)再灌注心律失常的效果。方法 :对 10 2例 AMI患者随机分为中西药治疗组和西药治疗对照组 ,每组 5 1例。中药治疗组采用针剂葛根素和脉安定静滴 ,对照组用极化液静滴 ;溶栓和其它治疗 2组相同 ,均采用常规方法。结果 :中西药治疗组心律失常较对照组显著减少 (P<0 .0 1)。综合评价中西药治疗组总有效率为 96 .1% ,对照组为 82 .4% ,2组有显著差异(P<0 .0 1)。结论 :葛根素和脉安定对 AMI再灌注心律失常有明显的防治效果。Objective:To investigate the preventive and therapeutic effects of puerarin(葛根素) and panangin(脉安定) early used on cardiac arrhythmia induced by reperfusion injury in patients with acute myocardial infarction(AMI).Methods:One hundred and two cases with AMI were randomly divided into two groups.The treatment group ( n =51) was treated with puerarin injection and panangin infused intravenously,but the control group treated with compound of glucoseinsulinpotassium.The thrombolytic and additional therapies were given to both groups simultaneously,the conventional therapy was given also to both groups.Results:The reperfusion arrhythmia(RA) was significantly decreased in treatment group compared to that in control group ( P <0 01).The total effective rate was 96 1% in treatment group and 82 4% in control group.There was significantly different between two groups( P <0 01).Conclusions:The study indicates that puerarin and panangin has obviously preventive and therapeutic efficacy on cardiac arrhythmia induced by reperfusion injury in patients with AMI.

关 键 词：急性心肌梗死 再灌注心律失常 葛根素 脉安定 治疗 

分 类 号：R542.22[医药卫生—心血管疾病] R541.7[医药卫生—内科学]