中草药治疗奶牛卵巢功能失调性不孕症及其对生殖内分泌的调控  

Effects of Chinese Herbal Medicine(Fufangxianyangtang)on Treating Infertile Cows with Ovary Function Disorder and Regulating the Reproductive Endocrine

作　　者：赵永前[1] 蒋兆春[1] 苏德辉[1] 戴鼎震[1] 瞿永前[1] 董晨红[1] 黄夺先[1] 

机构地区：[1]江苏省农业科学院畜牧兽医研究所,江苏南京210014

出　　处：《江苏农业学报》2001年第3期180-183,共4页Jiangsu Journal of Agricultural Sciences

基　　金：江苏省自然科学基金项目 (BK97189)

摘　　要：应用中草药治疗奶牛卵巢功能失调性不孕症取得了显著疗效。在此基础上 ,通过测定山羊灌服中草药“复方仙阳汤”前后促性腺素释放激素 (GnRH)、促卵泡素 (FSH)、促黄体素 (LH)、孕酮 (P4 )及 17β 雌二醇 (17β E2 )等生殖激素的含量变化 ,证明中草药有调控山羊生殖内分泌的作用。试验小白鼠在服用复方仙阳汤及单味中药(肉苁蓉、补骨脂、仙灵脾浸液 )后 ,子宫角外径厚度和子宫卵巢重量均较对照组 (服用 0 9%生理盐水 )高 ,表明上述中草药具有促进子宫、卵巢发育 ,促进发情、排卵的功能。给小白鼠肌注 0 2 5mg/d醋酸氢化可的松 10d后可成功地建立肾阳虚动物模型 。The experiment was designed to investigate the mechanism of the remarkable curative effect of Chinese herbal medicine on treating infertile cows with ovary function disorder.'Fufangxianyangtang' was treated to 313 infertile cows with ovary function disorder,and the effective percentage reached 92 97%(291/313)with the pregnancy rate of 86 30% within 3 estrous cycles.Changes of contents of GnRH,FSH,LH,P 4 and 17β E 2 in goat after treated with Fufangxianyangtang proved the herbal medicine was able to regulate reproductive endocrine in the infertile cows.Outer diameter thickness of uterus horn and ovary weight of mouse taken Fufangxianyangtang and envent herbal medicine('Roucongrong','Buguzhi','Xianlingpi')were significantly higher than those of mouse taken 0 9% normal saline(CK),which indicated that Chinese herbal medicine mentioned above could promote the development of uterus and ovary,and stimulate mouse to estrous cycle and ovulation.An animal model-deficiency of kidney yang established also proved there were some female hormone like active matters in Chinese herbal medicine.

关 键 词：奶牛 生殖内分泌 卵巢功能失调性不孕症 调控 中草药治疗 

分 类 号：S858.23[农业科学—临床兽医学] S853.51[农业科学—兽医学]