窒息新生儿脑损伤的早期防治  

Early prevention and treatment of brain injury in asphyxia newborn infant

作　　者：王雅娟[1] 秦苏康[1] 李丽[1] 朱萍[1] 

机构地区：[1]88医院妇产科,山东泰安271000

出　　处：《前卫医药杂志》2001年第2期114-115,共2页Qianwei Journal of Medicine & Pharmacy

摘　　要：目的　窒息新生儿心肺复苏后 ,由于缺血缺氧带来了一系列的全身性病理生理变化 ,其中脑病及脑出血是常见的较严重的并发症。为了提高治疗效果 ,我院产科对 112例窒息儿采取脑损伤早期药物预防和治疗临床观察。方法　窒息新生儿在出生后 2～ 6h给予鲁米那、水合氯醛交替应用 ,地塞米松与速尿交替应用 ,同时加用止血药治疗。结果　 112例窒息新生儿治愈 10 4例 ,抢救成功率 92 .86 % ,足月新生儿死亡率 0 .0 1%。结论　窒息新生儿早期应用鲁米那干预不但可以预防脑损伤 ,对已有脑病及脑出血的患儿也可以达到治疗效果。Objective After cardiopulmonary resuscitation of asphyxia newborn infant,systemic pathological changes were caused by ischemia and anoxia,among which brain disease and brain bleeding were common and more severe complications.To increase treatment effect,authors took early drug prevention and treatment,and clinial observation for 112 asphyxia newborn infants.Methods Luminal and chloral hydrate,and dexamethasone and frusemide were given alternatively,2～6h after birth of the infants,while hemostatics was added.Results The 104 infants were cured of brain injuries,successful emergency treatment rate was up to 92.86%,death rate of full term newborn infants was 0.10%.Conclusion Early intervention of Luminal in asphyxia newborn infants not only may prevent from brain injuries,but have therapeutical effects for the infants which suffered from brain disease and brain bleeding. [

关 键 词：新生儿窒息 新生儿 颅内出血 苯巴比采 缺血缺氧性脑病 

分 类 号：R722.12[医药卫生—儿科]