α-呋喃丙烯酸的合成研究  

Synthesis of α-Furylacrylic Acid

作　　者：刘秀娟[1] 王歌云[1] 孙凌峰[2] 

机构地区：[1]江西教育学院化学系,江西南昌330029 [2]江西师范大学化学系,江西南昌330027

出　　处：《精细化工》2001年第7期428-431,共4页Fine Chemicals

摘　　要：在吡啶介质中 ,以六氢吡啶为缩合剂 ,通过糠醛与丙二酸的Knoevenagel缩合反应合成了α 呋喃丙烯酸 ,并对影响产率的因素进行了研究。结果表明 ,当n(糠醛 )∶n(丙二酸 )∶n (吡啶 )∶n (六氢吡啶 ) =1 0 0 0∶1 40 0∶2 40 0∶0 0 2 5时 ,在 95℃下反应 2 5h ,呋喃丙烯酸的产率为92 8% ,质量分数为 99 5 %。In pyridine, α-furylacrylic acid was synthesized with furfural and malonic acid by Knoevenagel condensation reaction using piperidine as condensation agent. In addition, factors influencing the yield were studied. It was found that when n (furfural): n (malonic acid): n (pyridine): n (piperidine) = 1.0:1.4:2.4:0.025 and the reaction was carried out for 2.5 h at 95 °C, the yield of α-furylacrylic acid was 92.8% with 99.5% purity.

关 键 词：Α-呋喃丙烯酸 KNOEVENAGEL缩合反应 糠醛 丙二酸 合成 

分 类 号：TQ251.1[化学工程—有机化工]