不同周龄大耳白兔血液生理生化指标的测定  

Age-Related Changes in Hematological and Serum Biochemical Values of White Rabbits

作　　者：岳秉飞[1] 程水生[2] 杨果杰[3] 吴福林[2] 刘双环[1] 靳彦华[2] 左琴[1] 程君生[2] 邢瑞昌[1] 

机构地区：[1]国家啮齿类实验动物种子中心,北京100050 [2]中国兽医药品监察所,北京100081 [3]北京大学医学部,北京100083

出　　处：《中国兽药杂志》2001年第3期17-21,共5页Chinese Journal of Veterinary Drug

基　　金：北京科技基金!9549815000

摘　　要：为了明确大耳白兔中国兽药监察所封闭群的生物学特性 ,对其血液生理生化指标进行了测定。选 5、1 0及 1 3周龄的雄兔和雌兔 ,空腹采血测定红细胞、白细胞等 1 6项血液生理指标和血糖、总蛋白等 1 6项生化指标。 1 0周龄的红细胞数、白细胞数、红细胞压积和平均红细胞血红蛋白含量高于 5周龄和 1 3周龄 ,雌雄间血液生理指标无明显差异 ;血清丙氨酸转氨酶含量随着周龄的增加而升高 ,碱性磷酸酶则随着周龄的增加而下降。与日本大耳白兔相比 ,主要血液生理指标比较接近 ,丙氨酸转氨酶、白蛋白、尿素氮、直接胆红素等血液生化指标相近 ,其他指标有所不同。测定结果表明 ,该封闭群具有不同于日本大耳白兔 (Slc:JW/ CSK)The colony of white rabbits from National Institute for Control of Veterinary Bioproducts and Pharmaceuticals (NICVBP) is a new colony. In this paper, hematological and serum biochemical values in white rabbits were determined. Using male and female rabbits in 5, 10 and 13 weeks old, collected blood after 12h fast, 16 values in the hematology (RBC, WBC, PLT, HGB, etc.) and 16 values in biochemistry (ALT, AST, ALP, GLU,CHO, BUN, CRE, etc.) were determined. RBC, WBC, HCT and MCHC values in 10 week old were higher than 5 and 13 weeks old, there were no significant differences between male and female; ALT value was increased by age, but ALP value was decreased by age. Compared with Sla:JW/CSK rabbits, main hematological values and ALT, ALB, BUN and T.BIL values were approximate, but other values were different. These findings suggest that the NICVBP:JW rabbits has different characteristics with Slc:JW/CSK rabbtis.

关 键 词：家兔 血液生理指标 血液生化指标 大耳白兔 周龄 

分 类 号：S865.19[农业科学—野生动物驯养]