双黄连粉针剂与抗生素激素类药物配伍的实验研究  

Experimental Study on Compatibility of Shuanghuanglian Injection Powder, Antibiotics and Steroids

作　　者：薛华[1] 张淑梅[1] 何心[1] 郭宏声 

机构地区：[1]黑龙江省医院,黑龙江哈尔滨150036 [2]武警黑龙江省黄金一总队医院,黑龙江哈尔滨150086

出　　处：《黑龙江医学》2001年第8期577-578,共2页Heilongjiang Medical Journal

摘　　要：目的　为研究双黄连粉针剂与临床常用抗生素、激素类药物是否可以配伍使用。我们对双黄连粉针与抗生素、激素类及几种常用的急救用药配伍实验进行了研究。方法与结果　在室温条件下双黄连粉针剂在输液中与氨苄青霉素、头孢唑琳钠、地塞米松 ,按常规剂量配伍后 ,在 8h内无理化配伍禁忌现象 ,药液稳定 ,可以配伍使用 ;与氨基糖甙类抗生素、庆大霉素等按常规剂量配伍立即产生沉淀 ,不可配伍 ;同乳糖酸红霉素配伍与浓度有关 ,浓度 <0 6g时不产生沉淀 ,如按临床常用日剂量 1 2g时配伍即产生沉淀 ;与尼可刹米、山梗菜碱、阿拉明、多巴胺、速尿按常规剂量配伍后 ,在 5h内无理化配伍禁忌现象 ,药液稳定 ,可以配伍应用。Objective To study whether Shuanghuanglian injection powder has compatibility with antibiotics and steroids which are common used in clinic. Methods The Shuanghuanglian injection powder was dispensed with varied antibiotics and steroids separately to observe whether the solution was stable and clear or sedimentation for 8 h physically and chemically. Results The compatibility should be taken care of when Shuanghuanglian injection powder dispensed with inclined acid drugs.

关 键 词：双黄连粉针剂 抗生素 激素 配伍 

分 类 号：R942[医药卫生—药剂学] R289.1[医药卫生—药学]