2型糖尿病中医辨证分型与血浆内皮素及降钙素基因相关肽研究  

Study on Relationship Between TCM Syndrome Differentiation and Plasma Edothelin,Calcitonin Gene-related Peptide in Type 2 Diabetes

作　　者：李植延[1] 张荔群[1] 

机构地区：[1]福建中医学院中医系,福建福州350003

出　　处：《福建中医学院学报》2001年第3期1-4,共4页Journal of Fujian College of Traditional Chinese Medicine

摘　　要：为探讨 2型糖尿病中医辨证分型与血浆内皮素及降钙素基因相关肽的关系 ,检测血浆内皮素 ( ET)及降钙素基因相关肽 ( CGRP)含量 ,分析其与中医各证型的关系。结果显示 :1糖尿病各型患者血浆 ET值均较正常对照组明显增高 ,其中血瘀气滞组 >阴阳两虚组 >气阴两虚组和阴虚热盛组 ,而气阴两虚组与阴虚热盛组之间无明显差异。2糖尿病各型患者血 CGRP值均较正常对照组明显下降 ,其中血瘀气滞组和阴阳两虚组 <气阴两虚组 <阴虚热盛组 ,而血瘀气滞组与阴阳两虚组之间无明显差异。说明糖尿病患者中医辨证各证型的微观机制及病程演变与血管内皮细胞功能。To discuss the relationship between TCM syndrome differentiation and plasma edothelin(ET),calcitonin gene related peptide (CGRP)in type 2 diabetes,the contents of plasma ET and CGRP were measured and the relationship between the contents and syndrome differentiation was analyzed.The results showed as follows:①ET of TCM syndrome groups was obviously higher than that of the normal group,and the blood stasis with QI stagnation group(G1)was the first,deficiency of YIN and YANG group (G2)second,deficiency of QI and YIN group (G3) as well as YIN deficiency with excessive heat group (G4)last.There was no obviously different between G3 and G4.②CGRP of TCM syndromes was obviously higher than that of the normal group,and G4 was the first,G3 second,G1 and G2 last.There was no obviously different between G1 and G2.It indicates that the micro mechanism and course of illness of TCM syndromes in diabetes are closely related to the functional changes of endothelial cell and peptidergic nerves.\;

关 键 词：Ⅱ型糖尿病 辨证分型 内皮缩血管肽类 降钙素基因相关肽 肾虚 血瘀 

分 类 号：R259.8[医药卫生—中西医结合]