电极处理对葡萄糖传感器稳定性的影响  

Effect of Electrode Treatment on Stability of Glucose Sensor

作　　者：周松[1] 苟立[1] 冉均国[1] 孟宪伟[1] 

机构地区：[1]四川大学无机材料系,成都610065

出　　处：《分析化学》2001年第9期1008-1011,共4页Chinese Journal of Analytical Chemistry

基　　金：高等学校博士学科点专项科研基金;国家自然科学基金(No.69772039)资助项目

摘　　要：针对目前在共价键法固定葡萄糖氧化酶传感器过程中，存在影响传感器稳定性的封装、氧化和后处理3个问题，通过选择新的封装材料，进行多层复合封装，解决了因封装失效影响传感器稳定性的问题；研究了铂电极的氧化方法和氧化程度对传感器稳定性的影响，优化了铂电极的氧化工艺；采用了新的电极通电后处理方法。制得了性能良好的传感器，使电极的稳定性显著提高，经连续测试15天，传感器的相对活性为91％；存放3个月后，传感器的相对活性达到90％。Three processes such as encapsulation, oxidation and post-treatment have influenced on sensor stability in the covalent immobilization of glucose sensor. In the present paper, new encapsulation materials and multilayer-combined encapsulation have been found to eliminate the failure of encapsulation. In addition, the effect of oxidation method and oxidation extent of platinum electrode on the sensor stability was studied for optimizing the oxidation process of platinum electrode. We also used new electrode post-treatment under a constant potential. The result shows that glucose sensors with better performance have been fabricated and the stability of enzyme electrode is improved significantly. Sensor activity still reaches 91% after continuous operation for 15 days and relative activity remains 90% by dry storage of enzyme electrode for 3 months.

关 键 词：葡萄糖传感器 封装 铂电极 氧化 酶电极 后处理 稳定性 葡萄糖 电化学分析 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]