稳健回归解析紫外光度法同时测定磺胺甲噁唑和甲氧苄啶  

Simultaneous Determination of Sulfamethoxazole and Trimethoprim in Tablets with Robust Regression by Spectrophotometry

作　　者：耿新[1] 李井会[2] 高礼让[2] 朱秀慧[2] 

机构地区：[1]天津大学应用化学系,天津300072 [2]鞍山钢铁学院应用化学系,鞍山114002

出　　处：《分析化学》2001年第9期1036-1038,共3页Chinese Journal of Analytical Chemistry

摘　　要：磺胺甲噁唑和甲氧苄啶的紫外光谱严重重叠，本文构造和使用两个M估计的新的目标函数导函数(x)函数，并由此建立两个新稳健回归方法，以此解析重叠的吸收光谱，不经分离紫外分光光度法同时测定磺胺甲噁唑和甲氧苄啶，结果满意。为多组分同时测定提供了两个新稳健回归方法。Ultraviolet spectra of sulfamethoxazole and trimethoprim overlap seriously. Two derivative functions of target function of M e stimation have been constructed to resolve the overlapped spectra, and a robust regression method for the simultaneous spectrophotometric determination of sulfa methoxazole and trimethoprim was developed.\=

关 键 词：稳健回归 紫外光度法 磺胺甲恶唑 甲氧苄啶 药物分析 

分 类 号：O657.3[理学—分析化学]