运动性形体疲劳“肝肾亏虚”动物模型的实验研究  

An Experimental Study on Animal Model of Deficiency of the Liver and Kidney in Exercised Body-form Fatigue

作　　者：刘波[1] 邹明[1] 马建[1] 戴国钢[1] 罗小兵[1] 

机构地区：[1]国家体育总局成都运动创伤研究所,四川成都610041

出　　处：《中国中医骨伤科杂志》2001年第4期20-23,共4页Chinese Journal of Traditional Medical Traumatology & Orthopedics

基　　金：国家体育总局系统课题 编号 :( 1996) 2 699

摘　　要：目的 :建立运动性形体疲劳“肝肾亏虚”动物模型。方法 :采用电刺激 3周大强度运动训练兔模型。结果 :发现其体重、血睾、血红蛋白明显下降 ,血液流动性降低 ,腱围组织劳损 ,骨骼变形加大 ,疲劳性骨膜炎产生 ,肌腱韧带应力松弛明显增加 ,关节软骨平衡剪切模量下降。根据祖国医学和现代医学的理论 ,我们认为这是运动性形体疲劳“肝肾亏虚”的典型表现。Objective:To create the animal model of deficiency of the liver and kidney in exercised body-form fatigue.Methods:With the electric cage,the rabbits took run and jump exercise 360 times daily for 3 weeks.Results:After 1,2 and 3 weeks exercise,the body weight, serum testosterone,hemoglobin decreased significantly.The characteristics of hemorheology got wores at the end of 3rd week exercise. It is very clear images of fatigue periostitis observed radiologically. Under microscope,the overuse micro-damages were widespread in bone and peritendineum tissue.The properties of antideformation of tibia weakened after 3 weeks of exercise. The relaxation of flexor tendons and patellar ligaments increased.The shear modulus of tibia articular cartilage dropped after 2 and 3 weeks of exercise. Conclusion:According the theory of Chinese traditional medicine,we believe this is an animal model of deficiency of the liver and kidney in exercised body-form fatigue.

关 键 词：运动性形体疲劳 肝肾亏虚 血液流变学 生物力学 动物模型 

分 类 号：R255.5[医药卫生—中医内科学]