^(99)Tc^m标记的中枢神经系统受体放射性药物的设计方法及进展  

Design Methods and Recent Development of ^(99)Tc^m Labeled Receptor Radiopharmaceuticals for CNS Imaging

作　　者：贾红梅[1] 刘伯里[1] 

机构地区：[1]北京师范大学化学系,北京100875

出　　处：《同位素》2001年第2期95-106,共12页Journal of Isotopes

基　　金：国家自然科学基金资助项目 (2 0 0 710 0 5 )

摘　　要：综述了 99Tcm标记的中枢神经系统受体放射性药物目前的进展 ,着重讨论了不同受体放射性药物的设计方法及存在的问题。Recent developments of 99 Tc m labeled receptor radiopharmaceuticals for central nervous system (CNS) imaging are reviewed. The emphases are focused on how to design 99 Tc m labeled radiopharmaceuticals based on known structure activity relationship. The present problems of these radiopharmaceuticals and different design methods are also discussed.

关 键 词：^99TC^M标记 受体放射性药物 中枢神经系统 设计方法 锝99标记 

分 类 号：R817.51[医药卫生—影像医学与核医学]