PRESYNAPTIC Al ADENOSINE RECEPTOR-MEDIATED INHIBITION OF NOCICEPTIVE TRANSMISSION TO SPINAL DORSAL HORN NEURONS IN THE ADULT RAT  

PRESYNAPTIC Al ADENOSINE RECEPTOR-MEDIATED INHIBITION OF NOCICEPTIVE TRANSMISSION TO SPINAL DORSAL HORN NEURONS IN THE ADULT RAT

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作  者:Eiichi KUMAMOTO Hidemasa FURUE Megumu YOSHIMURA 

机构地区:[1]Department of Physiology, Saga Medical School 5-1-1 Nabeshima, Saga 849-8501, Japan

出  处:《神经解剖学杂志》2001年第B07期116-116,共1页Chinese Journal of Neuroanatomy

摘  要:Although intrathecal administration of adenosine analogues or A_1 adenosine receptor agonists is known to result in antinociception, this has not been examined yet at the cellular level. In the present study, we examined pharmacologically the actions of adenosine on spontaneous sensory transmission in substantia gelatinosa (SG) neurons of an adult rat spinal cord slice under the condition where a postsynaptic action of adenosine

关 键 词:成年大白鼠 脊髓背角神经 损伤感受传导 突触前抑制 A1腺苷受体调制性抑制 疼痛 

分 类 号:R402[医药卫生—临床医学]

 

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