虎杖根茎蒽醌类化合物细胞化学定位和含量测定(简报)  

HISTOCHEMICAL LOCALIZATION AND QUANTITATIVE ANYLYSIS OF ANTHRAQUINONES IN RHIZOME OF Polygonum cuspidatum

作　　者：刘文哲[1] 胡正海[1] 

机构地区：[1]西北大学植物研究所,西安710069

出　　处：《实验生物学报》2001年第3期235-241,共7页Acta Biologiae Experimentalis Sinica

摘　　要：虎杖(Polygonum cuspidatum Sidb.et Zucc.)为蓼科多年生灌木状草本。其根茎入药。主要化学成分有蒽醌、萘醌、酚类和多糖化合物;其中蒽醌类化合物是虎杖的主要药用有效成分,包括大黄素、大黄酚,大黄素甲醚和大黄酸等。虎杖的蒽醌类化合物具显著的抗病毒、抗菌和消炎作用;并可保护心肌,防止血栓形成,改善微循环,提高细胞免疫力,也是致癌基因转导信号的抑制因子。关于虎杖蒽醌类化合物细胞化学研究尚未见报道。刘文哲等曾对贯叶连翘分泌结构中金丝桃素和大黄中蒽醌类同化合物进行了组织化学研究。Anthraquinones were histochemically localyed and content were determined in rhizome of Polygonum cuspi-datum. Anthraquinones were located in the parenchyma cells of rhizome, including vascular ray, part of parenchyma cell in phloem, cortex and pith. Phelloderm and ray initial also accumulated a small amount anthraquinones. The content of total anthraquinones was highest in pith that consisted of parenchyma cells, and higher in bark (including phloem, cortex and periderm) than in xylem. The content of total anthraquinones was highest in three-year-old rhizome, and higher in biennial rhizome than in annual rhizome. It suggests that correlation exist between accumulation of anthraquinones and the growth age of rhizome.

关 键 词：虎杖 根茎 蒽酯类化合物 细胞化学定位 测定 

分 类 号：R284[医药卫生—中药学] R282.71[医药卫生—中医学]